Genetics Undergraduate research projects
Centers for Excellence in Genomic Science (CEGS) supports undergraduate summer research through the California Institute of Technology 's (Caltech) Summer Undergraduate Research Fellowship (SURF) and Minority Undergraduate Research Fellowship (MURF) programs. Applications are encouraged from students who wish to work in a modern academic research laboratory under the guidance of experienced scientists and engineers. The program will expose students to the excitement and opportunities of a research career in genomics and systems biology. This experience will provide excellent preparation for students interested in subsequently pursuing a Ph.D. Qualified minority undergraduates will work on diverse projects at the interface between genomics, imaging, developmental biology, and bioinformatics. In exceptional cases, high school students will also be considered for summer fellowships. Applicants must be U.S. citizens or permanent residents.
Post-Graduate Internship Program
Fellowships are available to fund minority M.D.s and Ph.D.s (or those pursuing M.D.s and/or Ph.D.s) to pursue genomic research. Stipends will be awarded to work in the laboratory of one of the four P.I.s on the CEGS grant and will have a duration of 2 to 3 years. Applicants must be U.S. citizens or permanent residents.
Project 1: Comprehensive spatiotemporal analysis of gene expression and function of the developing vertebrate embryo
We are developing techniques for performing in toto imaging that allow us to repeatedly image multiple vertebrate embryos throughout their embryonic development using in vivo time-lapse, confocal microscopy. We will generate a large collection of zebrafish lines using a transposon-based gene-trapping technology called "flip trapping". The FlipTrap cassette forms a functional fusion protein with a green fluorescent tag (GFP variant) when inserted into an intron. When exposed to cre-recombinase, the cassette assumes a second conformation, and generates a red fluorescent tag (RFP variant) gene trap and a mutant allele for the trapped gene. Thus, each flip trap line can be used to reveal the protein expression pattern (using the GFP fusion trap) and the mutant phenotype (using the RFP gene trap). Using in toto imaging, this information can be read out from the embryo in vivo and non-invasively. Once validated in the zebrafish, our goal is to apply this strategy to quail, an amniote that much more closely resembles the developing human embryo.
Project 2: Design of quantitative, multiplexed, "hybridization chain reaction" (HCR) amplifiers for in vivo imaging with active background suppression
We have designed and are testing a new in situ amplification approach based on the mechanism of hybridization chain reaction, in which fluorescently labeled DNA monomers self-assemble non-covalently into tethered "polymers" only when triggered by probes bound specifically to target mRNAs or proteins. The design principles underlying this approach promise to achieve specific and high resolution detection of multiple labels simultaneously.how to add corn to hamburger helper How to serve caviar? Dr pratts tips on how to write? How to close apps on iphone 13? How to reverse asin amazon tricks? How long does it take to get to the sun? Tumblr tips how to stop being sick? What does mensa stand for? What is the meaning of pang? How to litter train a kitten? Youtugbbe sf5 tips on how to do zangief super? What are trigger points? What is waifu mean? What does emp stand for? What sex tricks do women use? What does a heart flutter mean? How does tips etf work? How to measure height? What does choke her with a sea view meaning? What is histrionic personality disorder? What is the meaning of the metaphor in this paragraph? How to i tell him i like him? How to make draw string bags difficult tricks for drawstrings? How to pay for tips to parents? What does loki mean? What nationality is ariana grande? What is the meaning behind a christmas tree? What is the meaning of mercury in astrology? Tips on how to play fall out shelter? Blessed are those who mourn for they shall be comforted meaning? How to cook noodles? What are some tips for playing lottery? How to pair xfinity remote to box? How to get tricks in different areas of fortnite? What does disney own? What does eva mean? What does it mean to have a dream about someone? What is the meaning of womens day? When i die put my money in the grave meaning? Where to buy pool cue tips near me? What is the meaning of smells like teen spirit? Tips how to spraw paint from can? How to count macros? How to monetize youtube videos? What time does horror nights end? What does coucou in french mean? What does scada stand for? What is the meaning of tbd? What is the healthies tips for your nails? What does ascending mean? How to do easy magic tricks at home? how to thicken up runny cheest italian hamburger helper How to start a tips and tricks column? How to find duplicates in google sheets? How to wholesale houses? What are some good tips for a job interview? To get the latest tips, tricks, and how-to's, subscribe to our youtube channel.? How you recycle here tips reducing? helper t cells are important for activating which types of responses? How to unlock iphone without passcode? How to teach your dogs to do tricks? How to track changes in word? how to permanently remove new tab helper and shopping assistant from the browser What does plunder mean? Google how do you make a guinea pig do tricks? What does hair of the dog mean? What does it mean to have a chip on your shoulder? What is the term meaning pus in the fallopian tube? What does a coronary artery spasm feel like? How to make strawberry milk? How to calculate ovulation? What does patagonia mean? What does the name louise mean? What time is it in fiji? usb helper how to un pick 3ds How to defrost a turkey? How to do sparrow tricks? How long to keep saniderm on tattoo? How to cure sinus permanently at home? What does hyna mean? How to get rid of pimples fast? What can of tricks dogs do? What is fte? What time does best buy open on black friday? D2 an arsenal of tricks how to speed progress site:www.reddit.com? How to do tricks with a quadcoptor? What is mean median and mode? How to make grindstone? How to multiply square roots? What is the meaning of a ruby? What does you're mean? Tips on how to budget money? Why wont my fake tips stick to nail? What does cancel culture mean? How to turn off subtitles on disney plus? What does daniel mean? How to prepare for a phone interview? How to get your taste back from covid? Learn how to do bike tricks?
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